I received my shipment of Advanced Amino and instantly re-read all the material on the product, and the website just to reconfirm why I had made the purchase in the first place. While I procrastinated for two weeks about when I should start taking the product and wondering how noticeable the effect might be, I eventually uncapped a bottle one morning and finally started using Advanced Amino twice daily as prescribed. 7-8 days on and I can tell you my fatigue and general tiredness has gone, I'm feeling increasingly better on a daily basis and I have since received another product to sue in conjunction and the difference is like night and day. Energy levels are up, sleep patterns are better, moods are improved and for once I can actually notice the difference... long may that last for this 65.5 yr old guy.