I'm in my mid 50's and have been a truck driver for 35 plus years now. I'm not exaggerating whenever I say that the biggest obstacle for me being active, was pain, no matter what the task was. In fact, I avoided anything that involved any serious physical commitment. I have suffered from arthritis, hemorrhoids and inflammation for years. My Dr. was helping me manage my pain with opioid's for a decade which only masked the pain and caused unwanted side effects. Needless to say, I didn't have much to lose when I seen others with positive reviews about this product. I have been taking it for approximately a month and it has helped me. The 1st thing that I noticed was a vast improvement in my rectal area (lower digestive tract) then a reduction of the achy, dull pain and although I do have pain from past injuries that persist, I am moving better. I'm still in my 50's, but there's hope for a productive life with less pain and that's all I can realistically hope for from any supplement. I do take 2 in the morning and 1 in the afternoon daily and haven't had any adverse effects.