Beat Joint Pain with CUCUMBERS?

In clinical studies, this special cucumber extract reduced joint pain by a whopping 70%. It worked better than glucosamine-chondroitin. And it blocks the nasty enzymes that destroy your cartilage.

cucumbers

Cucumbers? Are you kidding? That’s the reaction I get when I tell my patients the news. Because you may not think the lowly cucumber packs much of a medicinal punch. But what you may not know is that a special type of cucumber has been used as medicine for over 3,000 years.

Roman doctors used it as far back as 77 B.C. to relieve insect bites. Cleopatra used it on her eyes to fight inflammation and puffiness. Christopher Columbus brought it on board his ships to keep his crew healthy.

And when modern-day scientists looked at this special type of cucumber, they were surprised, too. They found it contains 73 different compounds with powerful antioxidant and anti-inflammatory action.

Yet what really caught their eye was what these special compounds do for joint pain. They first noticed it in animal studies. Researchers took a group of animals that had pain and inflammation in their paws. They gave some of the animals these special cucumber compounds. Result?

The compounds reduced swelling and inflammation by up to 72%. And in as little as 2 hours!

Then, researchers tested these cucumber compounds on people with joint pain. The results were even more dramatic. They gathered dozens of adults between the ages of 40 and 75, all of whom had joint pain. They used three different methods of measuring: joint pain, stiffness and mobility. And they compared the results from 30 days to 6 months against a combination of glucosamine and chondroitin.

The group getting this cucumber compound felt their pain decrease by up to 70%. More than DOUBLE what people taking glucosamine-chondroitin felt.1 It worked twice as effectively as glucosamine-chondroitin at every single point in time in the study—from 30 days to six months.2

Researchers also found this special cucumber compound reduces a nasty enzyme called tumor necrosis factor alpha (TNF-a). TNF-a eats away at your cartilage and contributes to the destruction of your joints and joint pain.3,4,5,6 But in studies, this compound lowered TNF-a to ease inflammation.

The more they studied this special cucumber compound, the better it looked. It also contains a substance called fisetin. When researchers gave fisetin to lab animals, it slowed down age-related inflammation. It also reduced cartilage destruction and joint damage.

This special cucumber compound is also a good source of the mineral, silica. Silica strengthens the connective tissues (muscles, tendons, ligaments) that hold your joints together.

Now, you may be getting excited and ready to run out to the supermarket to stock up on cucumbers. But here’s the thing. You can’t get results like these just by eating cucumbers. Not the ones you find at the supermarket. It’s only available from certain heirloom cucumbers. Because only these cucumbers have enough of this special compound to make a difference. And even then, you’d have to eat pounds of them.

But recently, this special cucumber compound has been concentrated into a new ingredient called Q-Actin. I was so impressed by the research on Q-Actin that I called my friends at Advanced Bionutritionals and asked them to add it to their Advanced Joint Support formula right away. And to include the same amount used in the clinical studies.7

I’m thrilled they agreed. But they didn’t stop there. They also included these 6 other potent pain-fighters:

The Missing Mineral That Erases Joint Pain

Joint Pain

Could a single mineral reduce your joint pain?

The first tipoff came when scientists studied soil samples from around the world. They noticed that in areas where the soil contained very little of this mineral, up to 70% of people suffered from joint pain. But in areas where this mineral was plentiful, the rate of joint pain dropped to just 10% -- or even lower, down to zero!

That made scientists wonder if people with joint pain had lower levels of this mineral in their bodies. When they looked, that's exactly what they discovered! In fact in one study, people with joint pain in their hips had 50% less of this mineral than healthy patients.

Then they wondered… what if we gave people with joint pain more of this mineral? The results were astonishing. After just 7 days of taking this mineral, every single marker of painful inflammation was significantly reduced. The mineral also triggered the rebuilding of cartilage and bone. This amount of pain relief is amazing for a natural substance. Especially in such a short time!

So what is this miraculous mineral? It’s boron. A trace mineral found in nuts and leafy green vegetables. Unfortunately, most people don’t get enough of this vital trace mineral. That’s because our farmland soil is depleted and we just don’t eat enough fruits and veggies —the primary source of boron. That’s why taking boron can make such a difference for your joints. It acts as a natural anti-inflammatory. It eases swelling and discomfort. And it even…

Improves The Cushioning Between Your Joints

Knee Pain

Boron also promotes healthy levels of synovial fluid – the cushioning liquid between your joints. It helps your joints flex and move with ease.

Yet taking any type of boron won’t do. Because there’s a new type of boron that dramatically increases bioavailability and gives you fast, soothing relief. It’s a new, patented form of boron called Fruitex-B® Calcium Fructoborate.

Calcium Fructoborate can give you a better range of motion…better relief from inflammation…and better protection against free radicals that damage your hard-working joints.

Calcium Fructoborate works even better over time. In a 2-month study of people with joint pain, it gave substantial relief from pain and stiffness:

  • 78% of people had better knee movement;
  • 83% had less discomfort climbing stairs;
  • 88% felt less pain while walking.

It worked so well that 3 out of 4 people taking it were able to cut down on the pain pills they were using.

And there’s another big benefit to Calcium Fructoborate…

It Makes Glucosamine Work Even Better

When researchers gave this boron supplement to joint pain patients already taking glucosamine and chondroitin, they got an even bigger surprise...

Calcium Fructoborate helped glucosamine work better. 25% better for pain relief and cartilage healing! So if you’ve taken glucosamine before and haven’t felt a difference, not having enough boron could be why.

Both Q-Actin and Calcium Fructoborate go a long way toward relieving your joint pain. But you’ll also want to include…

The Natural Joint-Pain Reliever That Works in Just 2 Hours

Sometimes my patients complain that natural remedies for joint pain take too long to work. So here’s what I tell them…

There’s a natural remedy that works fast. It contains an active ingredient called salicin. Your body naturally converts salicin into salicylic acid, a pain-relieving compound that works quickly.8 This natural remedy is called white willow bark. White willow bark starts working in as little as 2 hours. It helps relieve your pain, repair your cartilage, and even helps protect your cells from further damage.

But I don’t suggest you use any type of white willow bark. Ordinary white willow bark contains just 15% salicin. But now, there’s a new form of white willow bark that contains a whopping 50% salicin. This extra-strength white willow bark makes all the difference. Patients of mine who have suffered for years with stiff, aching joints became pain free, thanks to this ultra-concentrated form of the herb!

In one study, people taking this concentrated white willow bark felt significant relief from their joint pain—as well as less swelling and better flexibility. Meanwhile, the people not getting white willow bark felt their pain get worse.9

In another study, white willow bark effectively relieved lower back pain. Nearly half the patients were pain-free in just 4 weeks. And researchers noted that white willow bark was especially good for people who couldn’t stomach conventional treatments.

In still another study, 78 people hospitalized with joint pain in their knees or hips got significant relief using white willow bark. And it’s not just the salicin that fights pain. White willow bark has plant compounds called flavonoids and polyphenols that add to its pain-relieving power.10 Plus, it’s well-tolerated and won’t churn up your stomach, even if you take it for a long time.11

In addition to white willow bark, you should also use…

Hand Pain

The Ancient Joint Healer That’s Now 60 Times Stronger

This pain-fighter has a history that goes back to the Bible.

It’s frankincense – now called boswellia. Boswellia has been used for centuries in Indian and Chinese medicine to maintain healthy joints. It works by increasing blood flow to your joints. It also slows down your body's production of chemicals called leukotrienes, which trigger inflammation.

The problem with Boswellia is that it’s very difficult to absorb. Yet now, this ancient balm has been made many times more powerful by modern science.

Scientists have created a new, concentrated form that contains 60 times the amount of boswellic acid. They call it 5-Loxin®. This new super boswellia works much better.

✔ It helps reduce 5-LOX, a nasty enzyme that contributes to inflammation;
✔ It clobbers another enzyme called MMP-3. MMP-3 eats away at the cartilage in your joints. Just a tiny amount of MMP-3 can cause agonizing pain. But 5-Loxin® keeps it at bay.

As a result, 5-Loxin® delivers…

Powerful Relief from Pain and Inflammation

In one study, people with joint pain received up to 250 mg. of 5-Loxin®. At the end of the study, they felt a 52% improvement in their pain and stiffness. And they started feeling less pain and stiffness in as little as 7 days.

In another study, people taking 5-Loxin® reduced their joint pain by up to 65%. Dozens of other studies show similar results. Are you starting to see why you want this “super Boswellia” called 5-Loxin® on your side, too? Fighting your joint pain day by day?

Now, if you only used the four nutrients I’ve mentioned so far, you’d be well on your way to complete pain relief. But I wanted to make sure Advanced Joint Support was the most effective formula we could possibly offer you. So that’s why we added 3 other joint pain superstars…

The Better Form of Turmeric

This popular Indian spice gives curry its distinctive flavor. It’s been used in Ayurvedic and Chinese medicine for centuries to fight inflammation and joint pain. You’ve probably heard of it—it’s turmeric. Turmeric is perhaps the most effective natural substance on earth at fighting COX-2, an enzyme that sends your body's inflammatory response into overdrive.12

Turmeric blocks other nasty enzymes, too, that eat away at your cartilage and increase your pain. These enzymes include interleukins and TNF-alpha. But the big problem with turmeric is that it goes through your body very quickly. It only lasts about 3 hours, then you have to take more.

Well now, scientists have solved this problem. They did it by “wrapping” turmeric inside tiny little fat bubbles called "phospholipids." This makes turmeric 20 times more absorbable. So more turmeric gets absorbed and reaches your aching joints and tissues.

Test results for this new form of turmeric – called Meriva® -- have been impressive. In one landmark study, Meriva® relieved joint pain as effectively as a popular conventional treatment while reducing stiffness and improving joint function. All without side effects.13

In another study, a group of people were given a conventional treatment for joint pain. A second group added Meriva® to their treatment. Result? In the group taking Meriva®14

✔ 63% were able to lower their use of other remedies;15
✔ 38% reported less stomach upset – probably because they were taking fewer pain pills;
✔ People taking Meriva® were able to walk 3 times farther on treadmill tests. It wasn't just their pain that ebbed away, either…

Meriva® also reduced something called C-reactive protein (CRP). CRP is a sign of inflammation.16 Too much CRP means your joints are getting worse. But Meriva® reverses that. People taking Meriva® showed a significant drop in their CRP levels.17

This is great news for joint pain sufferers! It means you can finally get all the inflammation-fighting power of turmeric – without having to take massive doses. Now let me tell you about another “must-have” nutrient for getting rid of your joint pain…

The Powerful Plant Compound That Fights Inflammation 3 Different Ways

For years, scientists have known that some plants contain powerful compounds called saponins. Saponins fight pain and inflammation. And one of the best sources for saponins is the Yucca plant.18

In one study, 6 out of 10 people who took Yucca as a supplement reduced their joint pain, stiffness, and swelling. In another study, the majority of people taking Yucca reported less pain and stiffness. All without any side effects.

The Yucca plant is also a rich source of resveratrol. As you may know, resveratrol helps you maintain a healthy heart and cholesterol. But did you know resveratrol also soothes inflammation? It's true. Resveratrol blocks COX-1 and COX-2 enzymes and other factors that can trigger joint swelling.

Yucca also contains polyphenols. Polyphenols are potent antioxidants and free-radical scavengers. They cool down the aches and pains in your joints and fight inflammation.19,20 All this makes Yucca a powerful ally in your fight against joint pain and inflammation. That’s why we included it in the new Advanced Joint Support.

There’s one more nutrient you must have in your battle against joint pain. Because you want…

Healthy New Cartilage and More Space Between Your Joints!

Knee Cartilage

This next nutrient is a vital building block for healthy cartilage. Researchers discovered it can even slow down the destruction of your joints – by helping you maintain more "space" between your bones. And they proved it with x-rays!

First, researchers used x-rays to measure the space between the joints of people with knee pain. Then, they gave people 1500 mg. of this special nutrient in placebo-controlled studies. At the end of the studies, people getting this nutrient had significantly more space between their knee bones. It was clear as day—right there on the x-rays!21

That's important, because having more space between your bones means less "bone-on-bone" grinding. That means less joint damage…less tenderness…and more relief from your pain!

So what is this nutrient? It's glucosamine. But if you’ve already tried glucosamine and haven’t noticed much of a difference, you may be taking the wrong kind. That’s because many joint formulas “cheap out.” They give you an inferior form of glucosamine so they can make more money.

But we only use the best type of glucosamine in Advanced Joint Support. Each daily dose contains a whopping 1500 mg of glucosamine sulfate 2KCl. Glucosamine sulfate 2KCl is a water-soluble form that's easier for your body to absorb. And it’s the same amount used in the clinical trials.

The 7-in-1 Formula For Both Fast Relief and Long-Lasting Healing

As you can see, new Advanced Joint Support gives you 7 of the most effective pain-relievers on the planet to support healthy joints and end your discomfort. Plus, they’re included in therapeutic levels to deliver the biggest benefits.

No other joint pain formula I know offers this unique combination—to give you both fast relief of your joint pain PLUS lasting healing of your cartilage and joints. You get…

  • Q-Actin - the patented new cucumber extract that helps prevent tumor necrosis factor alpha (TNF-a) from “eating away” at your cartilage;
  • White Willow Bark – to get faster relief from a natural remedy;
  • Fruitex-B® Calcium Fructoborate – the “missing mineral” that eases joint pain and improves the cushioning between your joints;
  • 5-Loxin® Boswellia – the ancient healer that gives you noticeable relief from pain in just 7 days;
  • Meriva Turmeric –now 20 times more absorbable than regular turmeric;
  • Yucca – the powerful plant compound that fights inflammation 3 different ways;
  • Glucosamine 2KCl – the superior glucosamine that helps maintain the space between your joints.

With this new Advanced Joint Support formula, you are really attacking joint pain from every angle. Leaving no stone unturned. No avenue for joint pain to escape!

Try New Advanced Joint Support Today at the Lowest Price!

You’d have a hard time finding all these nutrients at your local health food store. Especially Q-Actin or Fruitex-B® Calcium Fructoborate. And even if you could find them, you’d easily pay up to $132.49 a month to buy all 7 of them separately.

That's why I'm pleased that Advanced Bionutritionals has agreed to include them in their new Advanced Joint Support formula. You get all 7 – Q-Actin, White Willow Bark, Fruitex-B® Calcium Fructoborate, 5-Loxin® Boswellia, Meriva Turmeric, Yucca and Glucosamine 2KCl – for as little as $57.95 per month. Here’s how…

A one-month supply of Advanced Joint Support is just $69.95, plus $6.95 shipping and handling.

Plus, Several of These Nutrients “Ramp Up” the Power of Each Other…

✔ Combining cucumber extract with white willow bark boosts the bioactive compounds in both;
✔ Combining 5-Loxin® Boswellia with Meriva turmeric helps them both work better;22
✔ Combining Calcium Fructoborate with glucosamine gives you even more relief.

It really is a powerhouse combination!

Supplement Facts

For Even Bigger Savings

You can pay much less than that when you stock up with a 3-month supply of Advanced Joint Support. It’s just $188.85, plus shipping and handling is free! That’s a $21.00 savings off the regular price! Only $62.95 per bottle.

Advanced Joint Support Three bottles

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Down-to-the-Last Tablet Guarantee

Advanced Joint Support is one of Advanced Bionutritionals’ most popular products. If you want a chance to try it, you’d better place your order soon. In fact, I’d suggest you order at least 3 bottles—good for 3 months—to avoid disappointment.

And also because the longer you take Advanced Joint Support, the better it works. The formula helps dampen your joint pain within hours and continues to heal your cartilage and joints for months.

I’m so confident that this new Advanced Joint Support will finally relieve your joint pain that I’ve arranged for you to try it risk free. So go ahead. You be the judge.

Either way, you are protected by our 100% money-back guarantee. If you are not completely satisfied—thrilled!—send back the bottles within 90 days of your purchase. Even if they are empty. We’ll cheerfully refund every penny you paid—including shipping & handling. You only pay return shipping.

Get The Absolute Best Value

If you’re really serious about getting fast relief from your joint pain and long-lasting joint healing… AND saving the most money you can, then you should…

Ask for a 6-month supply of Advanced Joint Support for $347.70, plus shipping and handling is free! That’s a whopping $72.00 savings off the regular price! Just $57.95 per bottle.

Advanced Joint Support Six bottles

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Start Feeling the Relief in Hours… Keep Healing Your Joints for Months

Now you can get the best of both worlds. Fast-acting joint pain relief and long-lasting healing—without worrying about side-effects. You can also fight the nasty enzymes that are chewing up your joints and causing your pain. Get sweet relief from these culprits once and for all!

If you’re still on the fence, consider this: When you try new Advanced Joint Support, the worst that can happen is that you feel the same as you do now. And you can get a full refund – so you risk nothing.

But what if it does work better? You could feel your joint pain finally disappear. So you don’t even have to think about your joints anymore! You could heal your joints so thoroughly that you’d never even consider more extreme treatments. Instead, you’ll feel the strength, flexibility and comfort return to your joints once again.

Best of all…you could start doing all the things you love without a second thought. Whether it’s jogging, playing tennis, golf, going on long walks, dancing…you name it!

If you want your joints to stop hurting and start healing, you need to try this powerful new formula. That’s why I urge you to try Advanced Joint Support today. And why I recommend it to all my patients with joint pain. Try it today risk-free!

Yours for a pain-free life,

Frank Shallenberger

Frank Shallenberger, MD

P.S. Order below or call 1-800-791-3395 right now to take advantage of the remarkable joint-healing power of Advanced Joint Support. In just days, you'll feel new-found comfort and flexibility. Plus a wonderful new sense of possibilities for all that life offers!

P.S. Remember…you are completely protected by our 100% Money-Back Guarantee. You must feel a difference after taking Advanced Joint Support for a month or longer. Or it’s FREE. Simply return the bottle—even if it’s empty—within 90 days for a no-hassle refund. That's about as risk-free as it gets!

 



"Stopped pain in its tracks"

- Karen A., Advanced Joint Support Customer

Advanced Joint Support

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Advanced Joint Support Reviews

244 Reviews   |   4.3 Average Rating   |   90% Recommend This Supplement 

I can touch my toes! *
By Adele F. (Palm City, FL) - 4/30/2026
what I called "my cranky hip" is slowly becoming normal. after about 2 weeks of taking the supplement, I noticed I was able to tie my sneakers without so much pain. Encouraged, I continue taking supplement for about 2 months. I can easily tie my shoes and touch my toes. The pain in my cranky hip has gone from a 9-10 to a 3-4. I will continue !
  I Recommend This Supplement
  Verified Customer
It really works! *
By Margaret P. (Melbourne, FL) - 3/11/2025
This product was recommended to me by my doctor to aid in reduction of joint aches and pains. In a matter of days I could feel the difference.
  I Recommend This Supplement
  Verified Customer
Excellent For Joints *
By Sandra M. (Canada ) - 8/29/2024
I noticed a big difference in how I felt after taking this product, for only a few days. I hope that I can keep buying it, and use it regularly.
  I Recommend This Supplement
  Verified Customer
Comfortable Knees  *
By Simon P. (Ireland ) - 7/23/2024
Good product. Definitely helps my sore knees and ankles. Even just a few tablets with food works.
  I Recommend This Supplement
  Verified Customer
Great buy *
By Deborah M. (Tucson, AZ) - 6/23/2024
This has helped the general achiness I was experiencing in my joints, especially fingers and ankles. I don’t like to use many aids, so this does the trick.
  I Recommend This Supplement
  Verified Customer
I recommend this supplement. *
By MARILYN F. (SAN FRANCISCO, CA) - 6/9/2024
I am very pleased with the improvement in my knee joint. I can now walk up and down stairs without pain, in addition to taking longer walks without pain.
  I Recommend This Supplement
  Verified Customer
* Above are actual reviews from our customers. These customer’s statements may not reflect the typical purchaser’s experience and are not intended to represent or guarantee that anyone will achieve the same or similar results. The reviews should not be taken as the results a typical user will get. Your results may vary.

Disclaimers

  • Dr. Frank Shallenberger is compensated by Advanced Bionutritionals for his work in formulating and endorsing this product.
  • These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent a disease..

Sources

  • 1,2. Nash RJ, Azantsa BK, Sharp H, Shanmugham V. Clin Interv Aging. 2018 Oct 25;13:2119-2126. doi: 10.2147/CIA.S173227.
  • 3. Grunke M, Schulze-Koops H. Annals of the Rheumatic Diseases 2006;65:555-556.
  • 4,5. Jun-Ming Zhang, Jianxiong An, Int Anesthesiol Clin. 2007 Spring; 45(2): 27–37. doi: 10.1097/AIA.0b013e318034194e
  • 6. Thomas Mabey, Sittisak Honsawek, World J Orthop. 2015 Jan 18; 6(1): 95–105.doi: 10.5312/wjo.v6.i1.95
  • 7. Nash RJ, Azantsa BK, Sharp H, Shanmugham V. Clin Interv Aging. 2018 Oct 25;13:2119-2126. doi: 10.2147/CIA.S173227.
  • 8. Joseph C. Maroon, Jeffrey W. Bost,Adara Maroon. Surg Neurol Int. 2010 Dec 13;1: 80. doi: 10.4103/2152-7806.73804
  • 9. Schmid B, Lüdtke R, Selbmann HK, Kötter I, Tschirdewahn B, Schaffner W, Heide L.Phytother Res. 2001 Jun;15(4):344-50.
  • 10. Khayyal MT, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D. Arzneimittelforschung. 2005;55(11):677-87.
  • 11. Vlachojannis J, Magora F, Chrubasik S. Phytother Res. 2011 Jul;25(7):1102-4. doi: 10.1002/ptr.3386.
  • 12. Aggarwal BB, Harikumar KB.Int J Biochem Cell Biol. 2009 Jan;41(1):40-59. doi: 10.1016/j.biocel.2008.06.010.
  • 13. Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, et al.Clin Interv Aging. 2014 Mar 20;9:451-8. doi: 10.2147/CIA.S58535.
  • 14,15. Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, et al. Panminerva Med. 2010 Jun;52(2 Suppl 1):55-62.
  • 16. Sahebkar A.Phytother Res. 2014 May;28(5):633-42. doi: 10.1002/ptr.5045.
  • 17. Sahebkar A.Phytother Res. 2014 May;28(5):633-42. doi: 10.1002/ptr.5045.
  • 18. PR Cheeke,S Piacente, W Oleszek. J Inflamm (Lond). 2006 Mar 29.3:6.doi: 10.1186/1476-9255-3-6.
  • 19,20. Weinberg JB. Environ Health Perspect. 1998 Oct;106 Suppl 5:1131-7.
  • 21. Pavelká K, Gatterová J, Olejarová M, Machacek S, Giacovelli G, Rovati LC. Arch Intern Med. 2002 Oct 14;162(18):2113-23.
  • 22. Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N, Gasparyan S, et al.BMC Complement Altern Med. 2018 Jan 9;18(1):7. doi: 10.1186/s12906-017-2062-z.
Advanced Bionutritionals® products are manufactured in the USA from globally sourced ingredients.
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