I've been using Advanced Nerve Support for quite a while now, and it has brought much needed relief from the glycation I began to experience as a result of prior overindulgence in sugar, carbs, etc..Although now sugar, gluten, and dairy free, I continue to use this product, as the benfothiamine form of Vitamin B1 has been shown to greatly reduce, possible eliminate the glycation over time...it sure does for me! I am very grateful to Advanced BioNutritionals for providing this product to us..keep it coming, please!!