I am a small blond, blue eyed female which makes me a prime candidate for bone loss. Plus, I am 25 years past menopause! I have been taking Ultimate Bone Support for many years and as long as I remember to take the pill first thing in the morning, before I ingest anything else!!!! my bone density numbers stay up in the good zone. Getting the routine set to taking them everyday is the key and my GYN Doctor is very impressed with the results from my blood tests.