I started Advanced Amino in December. I've noticed 4 positive changes: 1) In October I went on a big hike and my right knee became very sore and had swelling. It affected my ability to work and I couldn't even walk the dog around the block for weeks. I tried pain killers, anti inflammatory pills, ice etc with no results. As a last resort I ordered Advanced Amino and started taking 3 pills in the morning and 2 in the evening in December. After the 1st week i noticed a reduction in pain. In 2nd week I noticed a reduction in swelling. By the end of 1 month my knee was 100% better. 2) Today I woke up to the fact that a pinched nerve in my foot that's been limiting my ability to walk long distances for two and a half years appears to be gone. Could that also be from Advanced Amino! It's the only new supplement I've been taking. 3) Also, my weight has been a consistent 212 for over 10 years. For the past month since finishing Advanced Amino I've been a consistent 202 - and that's after the holiday season meals! 4) And one last thing - I laugh about this one - I've got a bald spot on the back of my head. It's been shiney as a q ball and now there is some hair. Not a lot but more than the none that was there before. Is all of this due to Advanced Amino! It's the only new supplement I've taken during the time frame that I've noticed these positive changes so I can't point to anything else. I'm going to order more.